Commercial Aspects of Drug Discovery [2015-2016] [SEM 2]

High Throughput Drug Discovery [2015-2016] [SEM 2]

In Silico Drug Discovery [2015-2016] [SEM 2]

Modelling Metabolic Pathways [2015-2016] [SEM 2]

All cells rely on a complex interacting network of numerous metabolic pathways.  Each pathway in turn requires the concerted and well-regulated action of a team of enzymes.  These pathways with their component enzymes frequently make attractive drug targets.  Metabolic pathways in the parasitic protest Trypanosoma brucei (the causative agent of African sleeping sickness) will be used to illustrate how a combination of biochemical, genetic, control analysis and computer simulation approaches can be used to obtain useful working models of these pathways.

Systems Approach to Modelling Cell Signal Transduction [2015-2016] [SEM 2]