Week: 16 April - 22 April | Druggable Systems [2017-2018] [SEM2]

Home

Section outline

This week we will be looking at ways of genetically manipulating organisms in order to elucidate the functions of a potential drug target.
- Select activity A presentation to introduce the general themes of ...
  
  A presentation to introduce the general themes of the week
- Select activity Druggable Systems week 2 lecture inc. audio narration
  
  Druggable Systems week 2 lecture inc. audio narration File
- Select activity Videos and links that explain the concepts in more...
  
  Videos and links that explain the concepts in more detail
- Select activity The Science of Transgenic Technology Part 1 of 2 - Video
  
  The Science of Transgenic Technology Part 1 of 2 - Video URL
- Select activity The Science of Transgenic Technology Part 2 of 2 - Video
  
  The Science of Transgenic Technology Part 2 of 2 - Video URL
- Select activity Knockout mouse - Wikipedia page
  
  Knockout mouse - Wikipedia page URL
- Select activity Oncomouse - Wikipedia page
  
  Oncomouse - Wikipedia page URL
- Select activity Dominant negative mutation explained - Book chapter
  
  Dominant negative mutation explained - Book chapter URL
- Select activity Four articles expanding on the initial presentatio...
  
  Four articles expanding on the initial presentations
- Select activity PFKFB3 gene deletion causes vascular defects in vivo
  
  PFKFB3 gene deletion causes vascular defects in vivo File
- Select activity Genomic deletion of the PFKFB3 gene in mouse lung fibroblasts suppresses tumors
  
  Genomic deletion of the PFKFB3 gene in mouse lung fibroblasts suppresses tumors File
- Select activity Over-expression of PFKFB3 causes an increase in cell proliferation
  
  Over-expression of PFKFB3 causes an increase in cell proliferation File
- Select activity Transfecting cancer cells with dominant negative PFKFB3 reduces cell proliferation
  
  Transfecting cancer cells with dominant negative PFKFB3 reduces cell proliferation File
- Select activity This week's exercise
  
  This week's exercise
- Select activity Comparing enzyme active site pockets
  
  Comparing enzyme active site pockets Page
- Select activity This week's Collaborate session
  
  This week's Collaborate session
- Select activity Week 2 Collaborate session
  
  Week 2 Collaborate session
  
  23 April 2018, 9:00 AM - 10:00 AM

Section outline

A presentation to introduce the general themes of the week

Videos and links that explain the concepts in more detail

Four articles expanding on the initial presentations

This week's exercise

This week's Collaborate session