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Systems approach to modelling cell signal transduction

A major hope of the human genome project was that a fuller understanding of the genes associated with disease states would lead to a more rapid production of new lead compounds. In fact we also have to include the knowledge of how the biological organism responds to drugs. An aim of systems biology is to describe and understand the operation of complex biological systems. Current models can still only describe relatively simple systems, however the techniques associated with systems biology give useful insights to the drug discovery process.

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